Source: Ranked + player metaPatch: 16.17Window: patchRegion: allRank: emerald_plusQueue: ranked_soloSample: 41Updated 10/28/2026, 4:35:24 AM
Confidence: Medium-1.2% vs 50%41 games
Lane phases
AI heuristicLevels 1–2
Even
Senna and Milio trade evenly before spikes.
Levels 3–5
Milio edge
Play around ability cooldowns and wave control.
Level 6+
Milio edge
Ultimate timing often swings the next two waves.
Mid / late
Even
Side-wave and vision decide more than the raw lane matchup.
Why?
AI heuristicEven
- Sample win rate for Senna is 48.8% in this matchup.
Treat this as a Even matchup for Senna into Milio — prioritize cooldown windows and jungle tracking.
Do
- Track summoner spells and ultimate cooldowns before committing.
- Play for wave states that let you crash and reset safely.
Don't
- Don't force extended trades when key abilities are down.
- Don't ignore jungle timers when the lane is volatile.
Matchup build callout
Full builds →Most-played Senna page (Support): Deathfire Touch Build · 52.8% WR · 193 games
Skill order: Q › W › E
Keystones (player meta)
Most common keystones when senna faces milio in lookup-discovered matches.
Fleet Footwork4G100.0%
Deathfire Touch3G66.7%
Patch: 16.17Region: naRank: emerald_plusQueue: ranked_soloSample: 312Updated 10/22/2026, 1:02:15 PM