Source: Ranked + player metaPatch: 16.17Window: patchRegion: allRank: emerald_plusQueue: ranked_soloSample: 27Updated 9/11/2026, 8:20:26 PM
Confidence: Medium-1.9% vs 50%27 games
Lane phases
Levels 1–2
Even
Samira and Vayne trade evenly before spikes.
Levels 3–5
Vayne edge
Play around ability cooldowns and wave control.
Level 6+
Vayne edge
Ultimate timing often swings the next two waves.
Mid / late
Even
Side-wave and vision decide more than the raw lane matchup.
Why?
Sample-basedEven
- Sample win rate for Samira is 48.1% in this matchup.
Treat this as a Even matchup for Samira into Vayne — prioritize cooldown windows and jungle tracking.
Do
- Track summoner spells and ultimate cooldowns before committing.
- Play for wave states that let you crash and reset safely.
Don't
- Don't force extended trades when key abilities are down.
- Don't ignore jungle timers when the lane is volatile.
Matchup build callout
Full builds →Most-played Samira page (ADC): Conqueror Build · 42.7% WR · 96 games
Skill order: Q › E › W
Keystones (player meta)
Most common keystones when samira faces vayne in lookup-discovered matches.
Conqueror1G0.0%
Patch: 16.17Region: naRank: emerald_plusQueue: ranked_soloSample: 97Updated 9/11/2026, 8:18:15 PM