Source: Ranked + player metaPatch: 16.17Window: patchRegion: allRank: emerald_plusQueue: ranked_soloSample: 24Updated 10/28/2026, 4:35:05 AM
Confidence: Medium±0% vs 50%24 games
Lane phases
AI heuristicLevels 1–2
Even
Heimerdinger and Karthus trade evenly before spikes.
Levels 3–5
Even
Play around ability cooldowns and wave control.
Level 6+
Even
Ultimate timing often swings the next two waves.
Mid / late
Even
Side-wave and vision decide more than the raw lane matchup.
Why?
AI heuristicEven
- Sample win rate for Heimerdinger is 50.0% in this matchup.
Treat this as a Even matchup for Heimerdinger into Karthus — prioritize cooldown windows and jungle tracking.
Do
- Track summoner spells and ultimate cooldowns before committing.
- Play for wave states that let you crash and reset safely.
Don't
- Don't force extended trades when key abilities are down.
- Don't ignore jungle timers when the lane is volatile.
Matchup build callout
Full builds →Most-played Heimerdinger page (ADC): Conqueror Build · 47.2% WR · 36 games
Skill order: Q › W › E
Patch: 16.17Region: naRank: emerald_plusQueue: ranked_soloSample: 45Updated 10/22/2026, 1:02:15 PM